Dermapen 4 Microneedling Pen & Replacement Cartridges
The Complete Guide to the World's Most Advanced Microneedling System and Its 16-Needle Cartridges
The Dermapen 4™ microneedling pen is a flagship professional microneedling device that combines Advanced Oscillating Vertical Needle™ (AOVN) technology, a revolutionary 16-needle cartridge system, RFID smart cartridge recognition, Bluetooth connectivity, and dual power operation — one of the most advanced microneedling pens available today. Available now at genuine-product pricing from our store, with free worldwide shipping and full after-sales support.
This page covers everything you need to know: what the Dermapen 4 is, how the device works, which replacement cartridges it uses, how to choose the right Dermapen 4 cartridges for your practice, how it compares with Dr.Pen devices, and where to buy genuine Dermapen 4 products.
Disclaimer: The Dermapen 4 is a professional microneedling device intended for use by trained practitioners. This page is for informational purposes and does not constitute medical advice. Product information is based on the manufacturer's official published specifications; specifications and pricing are subject to change.
What Is the Dermapen 4 Microneedling Pen?
The Dermapen 4™ is a next-generation professional microneedling device. Unlike traditional dermal rollers or conventional electric microneedling devices, the Dermapen 4 uses patented Advanced Oscillating Vertical Needle™ (AOVN) Technology to create controlled, perfectly vertical micro-channels in the skin with exceptional accuracy. This vertical insertion minimizes unnecessary skin trauma, reduces drag, and promotes more uniform collagen induction while improving patient comfort throughout the procedure.
It is the world's first fully digital microneedling device, combining:
- Bluetooth connectivity for firmware updates, device registration, and warranty management
- Built-in RFID needle cartridge technology that automatically recognizes genuine Dermapen 4 cartridges and calibrates the device for precise, drag-free performance
- Dual power operation (cordless battery or corded mains power) for complete treatment flexibility
- A digital display with one-touch integrated settings for complete procedural control
The Dermapen 4 glides over the skin creating millions of fine, vertical fractional channels up to 104% faster than other microneedling pens, and these channels can carry up to 80% more topical nutrients deeper into the skin. The micro-injuries trigger the skin's natural repair process, increasing collagen and elastin production and visibly improving a wide range of skin concerns.
What skin concerns can Dermapen 4 address?
Dermapen 4 is commonly used by qualified practitioners to improve the appearance of:
- Fine lines and wrinkles
- Acne and post-acne scarring
- Surgical and traumatic scars
- Stretch marks
- Enlarged pores
- Uneven skin texture
- Sun-damaged skin
- Hyperpigmentation
- Skin laxity
- Hair thinning and scalp rejuvenation
Dermapen 4 Microneedling Pen — Core Features
| Feature | Dermapen 4™ Specification |
|---|---|
| Cartridge system | Revolutionary 16-needle cartridge (33G, medical-grade stainless steel, gamma-sterilised, single-use) |
| Needle depth | Digital adjustment up to 3.0 mm with automatic speed and depth calibration |
| Needle motion | Advanced Oscillating Vertical Needle™ (AOVN) Technology — perfectly vertical entry and exit |
| Speed | Up to 1,920 punctures per second — up to 104% faster than comparable devices |
| Nutrient delivery | Micro-channels carry up to 80% more topical nutrients deeper into the skin |
| Exclusive mode | Dedicated Scar Treatment (ST) Setting — the only microneedling device with a built-in scar treatment mode |
| Smart cartridge system | Built-in RFID — automatic recognition and calibration of genuine Dermapen cartridges; usage tracking for safety compliance |
| Safety technology | Anti-Contamination Management™ (ACM) — no fluid backflow, no cross-contamination, no drag; AOVN retention valves for regulated suction release |
| Power | Dual power: cordless battery or corded mains operation |
| Connectivity | Bluetooth enabled; syncs via the Dp DOCK™ for updates, registration, and warranty management |
| Display | Digital display with one-touch integrated settings |
| Regulatory status | FDA-cleared for the treatment of facial acne scars (US); CE-marked for EU markets |
Why professionals choose the Dermapen 4
- Faster, more comfortable treatments — millions of vertical micro-channels created up to 104% faster than comparable pens, with less pain and shorter treatment times
- Exclusive Scar Treatment Setting — a dedicated, automatically calibrated mode (up to 3.0 mm depth) specifically developed for scar revision: acne scars, surgical scars, traumatic scars, and stretch marks
- Genuine-cartridge verification — RFID technology confirms authentic Dermapen cartridges, ensuring consistent, calibrated performance treatment after treatment
- Hygiene you can trust — Anti-Contamination Management™ prevents fluid backflow and cross-contamination, supporting practitioner and patient safety
- Complete treatment platform — pairs with genuine Dermapen 4™ cartridges and professional post-procedure skincare protocols for end-to-end treatment workflows
- Ergonomic, lightweight handpiece — engineered to reduce fatigue during extended treatment sessions
Buy the Dermapen 4 Microneedling Pen
Dermapen 4 Replacement Cartridges
Every Dermapen 4 treatment uses a sterile, single-use 16-needle cartridge — the same cartridge technology used in professional clinics worldwide. Each Dermapen 4 replacement cartridge contains 16 ultra-fine, 33-gauge, medical-grade stainless steel needles that are gamma-sterilised for safety and hygiene.
Why the 16-needle cartridge?
The revolutionary 16-needle configuration is engineered to be the ideal balance of treatment intensity, coverage speed, and client comfort:
- More channels per pass — 16 precisely spaced needles create more controlled micro-channels in less time, improving treatment efficiency and consistent clinical outcomes
- Smoother glide, less pain — the optimized needle arrangement allows the cartridge to glide over the skin, creating more channels with noticeably less discomfort than conventional cartridges
- Clean vertical insertion — designed for perfectly vertical entry and exit with minimal epidermal damage and no dragging or tearing of tissue
- Optimal for scar revision and texture work — the 16-pin configuration is especially effective for scar revision, enlarged pores, uneven skin texture, and collagen induction procedures
- Single-use sterility — individually sealed disposable cartridges maintain hygiene and treatment safety for every patient
RFID smart cartridge recognition
The Dermapen 4's built-in RFID technology automatically recognizes genuine Dermapen 4 cartridges and calibrates the device for each one. This delivers:
- Automatic calibration for precise, consistent needle penetration
- Drag-free, smooth operation
- Safety verification that the cartridge is authentic
- Usage tracking for safety compliance
Cartridge compatibility
- Compatible with: Dermapen 4™ (the same 33G 16-needle cartridge technology used in professional clinics worldwide)
- Not compatible with: myDermapen (per the manufacturer's official guidance, these cartridges are not suitable for myDermapen)
Buy Dermapen 4 Replacement Cartridges
Dermapen 4 Cartridge Types Explained
Unlike Dr.Pen devices, which offer multiple needle-pin configurations (such as 12-pin, 18-pin, or 36-pin cartridges), the Dermapen 4 uses a single, unified 16-needle cartridge system. The 16-needle configuration is the only cartridge type designed for the Dermapen 4 — it is engineered to deliver the optimal balance of penetration efficiency, coverage speed, and patient comfort, so there is no need to choose between different pin counts.
What varies is the packaging size and purchase format, which affects cost per cartridge and how you manage inventory:
| Cartridge format | Contents | Best for |
|---|---|---|
| Standard 5-pack (manufacturer packaging) | 5 gamma-sterilised, single-use 16-needle cartridges | Practitioners starting out, verifying workflow, or carrying a small clinic inventory |
| Bulk 100-pack (16 Pins for Dermapen 4) | 100 gamma-sterilised, single-use 16-needle cartridges | Busy clinics and professionals running multiple daily procedures — lowest cost per cartridge, fewer reorder interruptions |
Key points about Dermapen 4 cartridges
- One needle type, one standard — the Dermapen 4 accepts only the 16-needle cartridge system; there are no alternative pin configurations to select, which simplifies ordering and training
- Always single-use — each cartridge is designed for one procedure per patient; never reuse or re-sterilise cartridges
- RFID-verified authenticity — the device only calibrates for genuine Dermapen cartridges, protecting treatment quality and safety
- 33G ultra-fine needles — fine enough for comfortable facial and sensitive-area work, robust enough for scar revision and body treatments at up to 3.0 mm depth
How to Choose Dermapen 4 Cartridges
Choosing the right Dermapen 4 cartridges is straightforward once you understand your procedure volume and hygiene requirements.
1. Match quantity to procedure volume
- Estimate sessions per month. A standard facial treatment typically uses 1–2 cartridges per session depending on treatment area and protocol. A full body or scalp procedure may use additional cartridges.
- Plan for courses of treatment. Most microneedling protocols run in a series (for example 3–6 sessions spaced 4–6 weeks apart). Multiply sessions by cartridges per session to size your order.
- Buy bulk for continuous practice. If you run procedures daily, the 100-pack delivers the lowest cost per cartridge and eliminates mid-week stockouts. If you are a solo practitioner with low volume, start with a 5-pack to validate your workflow.
2. Always use sterile, single-use cartridges
- Every Dermapen 4 cartridge is gamma-sterilised and individually sealed. Open a fresh cartridge for every patient and dispose of it after the procedure.
- Never reuse cartridges — single-use design is a core part of the Dermapen 4's Anti-Contamination Management™ safety standard.
3. Verify genuine cartridges
- The Dermapen 4's RFID system recognizes genuine Dermapen cartridges. If a cartridge is not recognized, the device will not calibrate to it — protect treatment quality by sourcing cartridges from authorized suppliers only.
- Purchase from trusted channels (such as the official store links on this page) to guarantee authentic, RFID-compatible cartridges.
4. Store cartridges correctly
- Keep sealed cartridges in a cool, dry place away from direct sunlight and moisture.
- Check the expiry date before use and discard any cartridge with damaged sterile packaging.
Dermapen 4 vs Dr.Pen: An Objective Comparison
Both Dermapen 4 and Dr.Pen are respected names in microneedling, but they are designed for different users and budgets. The comparison below is based on published specifications and current store pricing, presented objectively so you can match the device to your practice or personal skincare workflow.
| Feature | Dermapen 4 | Dr.Pen A11 | Dr.Pen M9 (2026) | Dr.Pen M8S |
|---|---|---|---|---|
| Positioning | Professional flagship — world's first digital microneedling device | Professional / advanced user flagship | Professional / home advanced | Professional |
| Cartridge system | 16-needle, 33G, gamma-sterilised, RFID-verified | 18-pin disposable cartridges | 18-pin disposable cartridges | 18-pin disposable cartridges |
| Max needle depth | Up to 3.0 mm with automatic calibration | 0 – 2.5 mm | 0 – 2.5 mm | 0 – 2.5 mm |
| Max speed | Up to 1,920 punctures/sec (up to 104% faster than comparable pens) | 18,000 RPM, 6 speed levels | 6 speed levels | 16,000 RPM, 6 speed levels |
| Speed settings | One-touch digital settings | 6 levels, digital display | Digital display | 6 levels, digital display |
| Power | Dual power: cordless battery + corded mains | Wireless, 800 mAh | Wireless | Wireless, 380 mAh |
| Smart features | RFID cartridge recognition, Bluetooth, exclusive Scar Treatment (ST) setting, Dp DOCK sync | Standard digital display | Standard digital display | Standard digital display |
| Safety technology | Anti-Contamination Management™ (ACM), retention valves | Anti-backflow cartridge design | Standard | Standard |
| Regulatory status | FDA-cleared (US, facial acne scars); CE-marked (EU) | Varies by market | Varies by market | Varies by market |
| Store price (USD) | $699.00 | $249.00 | $149.00 | $115.00 |
Speed and depth figures are as published by each manufacturer. Dr.Pen figures per the Dr. Pen model specifications; Dermapen 4 figures per the manufacturer's official specifications.
Which should you choose?
Choose the Dermapen 4 if you are a clinic or professional who wants:
- The most advanced microneedling technology on the market — Bluetooth, RFID smart cartridges, and digital calibration
- A dedicated Scar Treatment (ST) mode with up to 3.0 mm auto-calibrated depth, ideal for acne and surgical scar revision
- FDA-cleared status for facial acne scar treatment and CE-marking for EU markets
- A premium, fully digital treatment platform backed by professional clinical protocols
Choose a Dr.Pen model if you want:
- Exceptional value — Dr.Pen flagships cost a fraction of the Dermapen 4 while offering adjustable speed and depth (0–2.5 mm)
- A wide range of models across price points (from $99 to $249) to match your experience level and budget
- Flexible cartridge options with multiple pin configurations to suit different treatment styles
- A device that works well for both professional studios and advanced home use
Both systems deliver proven microneedling results. The right choice depends on your budget, your treatment goals (especially whether you need dedicated scar-revision technology), and whether smart-device features such as RFID and Bluetooth matter to your workflow.
Dermapen 4 FAQ
What is the Dermapen 4?
The Dermapen 4 is a flagship professional microneedling pen. It uses Advanced Oscillating Vertical Needle™ (AOVN) technology to create controlled vertical micro-channels, helping to improve the appearance of fine lines, wrinkles, scars, enlarged pores, pigmentation, and overall skin texture. It is the world's first fully digital microneedling device, featuring Bluetooth, RFID smart cartridges, dual power, and an exclusive Scar Treatment setting.
What cartridges does the Dermapen 4 use?
The Dermapen 4 uses the revolutionary 16-needle cartridge system: 16 ultra-fine, 33-gauge, medical-grade stainless steel needles that are gamma-sterilised and single-use. The device's built-in RFID technology automatically recognizes genuine Dermapen 4 cartridges and calibrates the device for precise, drag-free performance.
Can I use Dr.Pen cartridges on the Dermapen 4?
No. The Dermapen 4 is designed exclusively for genuine Dermapen 16-needle cartridges. Its RFID system recognizes and calibrates only authentic Dermapen cartridges, so Dr.Pen or other third-party cartridges will not work correctly and should not be used.
How deep can the Dermapen 4 needle go?
The Dermapen 4 offers digital depth adjustment up to 3.0 mm, with automatic calibration of speed and depth. The exclusive Scar Treatment (ST) setting automatically optimizes depth, speed, and oscillation pattern for scar revision procedures.
How fast is the Dermapen 4 compared with other microneedling pens?
According to the manufacturer's published specifications, the Dermapen 4 creates millions of fine, vertical fractional channels up to 104% faster than other microneedling pens — up to 1,920 punctures per second — which shortens treatment time and improves patient comfort. Its micro-channels can also carry up to 80% more topical nutrients deeper into the skin.
Is the Dermapen 4 FDA cleared?
Yes. The Dermapen 4 is FDA-cleared for the treatment of facial acne scars in the US, and it is CE-marked for EU markets.
How many cartridges do I need per treatment?
A standard facial treatment typically uses 1–2 cartridges, depending on the protocol and treatment area. Each cartridge is single-use and must be replaced for every patient. Body or scalp procedures may require additional cartridges.
How many sessions of Dermapen 4 microneedling are typically needed?
Most microneedling protocols run in a series of 3–6 sessions spaced approximately 4–6 weeks apart, depending on the skin concern being addressed. Your practitioner will design a personalized treatment plan based on your skin and goals.
Is Dermapen 4 microneedling painful?
The Dermapen 4 is engineered for comfort. The 16-needle cartridge glides over the skin creating more channels with less pain than conventional devices, and the faster treatment speed reduces overall procedure time. A topical anesthetic is commonly used in clinical protocols for deeper treatments.
Is the Dermapen 4 for home use?
The Dermapen 4 is a professional device designed for trained practitioners and clinics. If you are considering microneedling at home, consult a professional to determine the appropriate device and protocol for your skin.
What is included with the Dermapen 4 pen?
The Dermapen 4 device is sold as the professional treatment system, which includes the handpiece, its dual-power system, and Dp DOCK™ syncing for device updates, registration, and warranty management. Cartridges are sold separately. Check the product listing for full package contents.
Do I need to register my Dermapen 4?
Yes — we recommend syncing your Dermapen 4 regularly via the Dp DOCK™. Docking automatically performs a sync, ensures the device is up to date, and supports registration and warranty management.